منابع مشابه
Lymphocytosis: T-cell large granular lymphocyte leukemia.
A 50-year-old female with low-grade chronic anemia and no other medical problems was evaluated when her hemoglobin fell to 8.2 g/dL. She had no adenopathy or hepatosplenomegaly. Her white cell count was 7.7 109/L with a lymphocyte count of 6.2 109/L, platelets 498 109/L, and reticulocyte count that was normal. Serum electrophoresis and rheumatoid factor were negative and ANA was weakly positive...
متن کاملLow-dose methotrexate in PAH related to T-cell large granular lymphocyte leukaemia.
T-cell large granular lymphocytes (LGLs) are a morphologically distinct subset of normal peripheral blood mononuclear cells classified into two major lineages based on the presence of the CD3 receptor: CD3+ lymphocytes and CD3natural killer cells. The revised European-American classification of lymphoid neoplasms [2] considers clonal proliferation of these cells, or LGL leukaemia (as proved by ...
متن کاملAssociation of pure red cell aplasia with T large granular lymphocyte leukaemia.
AIM To define the relation between T large granular lymphocyte (T-LGL) leukaemia and pure red cell aplasia in Chinese patients. METHODS Patients with T-LGL leukaemia were identified from a consecutive series of Chinese patients with chronic lymphoproliferative disorders. The diagnosis of T-LGL leukaemia was based on typical morphological and immunophenotypical features, and confirmed by the d...
متن کامل[Large granular lymphocytic leukaemia].
BACKGROUND Large granular lymphocytic leukaemia (LGL-leukaemia) is considered a rare disease. LGL-leukaemia is usually of the T-cell type, but a minority displays an NK-cell phenotype. Incidence and prevalence are unknown. MATERIAL AND METHODS We identified patients with LGL-leukaemia (with well-defined diagnostic criteria) diagnosed at Rikshospitalet University Hospital between 01.10.2001 an...
متن کاملLeukaemia of natural killer cell large granular lymphocyte type with HLA-DR-CD16-CD56bright+ phenotype.
The case is reported of a 45 year old woman with the rare leukaemia of natural killer cell large granular lymphocyte (NK/ LGL) type. Cytometric analysis of leukaemic blasts showed that they were positive for CD2, CD38, and CD56 antigens but negative for a series of antigens including CD3, CD7, CD16, and HLA-DR. Rearrangements of the beta T cell receptor, and heavy and kappa immunoglobulin genes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/37932